Meanwhile, Captain Picard and his crew are ravaged by a highly contagious virus that Wesley Crusher and his friends contract during a field trip. At the same time, the ship is needed in the Neutral Zone to ward off hostile Romulan Warbirds.

After the away team leaves, the Angel One fugitives are discovered and sentenced to death. Despite the fact that it would violate the Prime Directive, Commander Riker prepares to beam the fugitives to the safety of the U.S.S. Enterprise. However, Dr. Crusher prohibits all boarding of the prisoners, except for the android Data, fearing the crew will be exposed to the virus.

As Dr. Crusher discovers an antidote for the virus, Riker fights to save the fugitives' lives. Despite the fact that he's a male, Riker's wisdom impresses the Angel One leader, who decides not to execute the fugitives. Instead, she exiles them to a remote area of the planet where they can live as they please. Pleased with their success, Riker and the rest of the U.S.S. Enterprise crew race off to thwart the Romulans.

"Justice" - In order to save Wesley from the death penalty for (accidentally) violating one of the Edo laws.

"Angel One" - The crew barely managed to save the survivors of a Federation ship from death for trying to change the society of Angel One.

"Pen Pals" - Data communicates with a girl whose planet was slowly self-destructing.

"Up The Long Ladder" - Picard essentially forced the clone race to live and breed with the Bringloidi, despite the strong resistance of the clone race and the fact that this would completely destroy the non-sexual nature of the clone race.

"The Ensigns of Command" - The Enterprise manages to delay a Sheliak vessel from destroying a Federation colony on Tau Cygna Five, even though the planet is part of the Sheliak Corporate.

"Who Watches The Watchers" - The Enterprise treats a Mintakan person for serious injuries as a result of a Federation observation post's cloaking device's failure, ending with that race believing Picard was a god.

"The High Ground" - The Enterprise engages in a commando raid in order to rescue Captain Picard and Beverly Crusher on a warring world.

"Legacy" - The commando raid might have radically changed the balance of power on the planet.

"First Contact" - The Enterprise contacts a planet in order to rescue Commander Riker